Assistant Professor Shovanlal Gayen, PhD

Dr. Harisingh Gour Central University

Department of Pharm. Sciences

Sagar, India.

 

PhD Thesis:

Functional and structural characterization of the stalk subunits F and H of the methanogenic A1AO ATP synthase. Degree in 2010

Publications:

  1. Debnath, B., Gayen, S., Bhattacharya, S., Samanta, S., and Jha, T. (2003) QSAR study on some Pyridoacridine Ascididemin Analogues as antitumor agents. Bioorg. Med. Chem. 11, 5493-5499

  2. Debnath, B., Gayen, S., Naskar, S. K., Roy, K., and Jha, T. (2003) Quantitative Structure-Activity Relationship Study on Some Azidopyridinyl Neonicotinoid Insecticides for Their Selective Affinity Towards the Drosophila Nicotinic Receptor Over Mammalian alpha(4)beta(2) Receptor Using Electrotopological State Atom Index. Drug. Des. Discov, 18, 81-89

  3. Gayen, S., Debnath, B., Samanta, S., and Jha, T. (2004) QSAR Study on Some Anti-HIV HEPT Analogues Using Physicochemical and Topological Parameters. Bioorg. Med. Chem.12, 1493-1503

  4. Samanta, S., Srikanth, K., Banerjee, S., Debnath, B., Gayen, S., and Jha, T. (2004) 5-N-Substituted-2-(Substituted Benzenesulphonyl) Glutamines as Antitumor Agents II: Synthesis, Biological Activity and QSAR Study. Bioorg. Med. Chem, 12, 1413-1423

  5. Debnath, B., Gayen, S., Basu, A., Srikanth, K., and Jha, T. (2004) Quantitative Structure-Activity Relationship Study on Some Benzodiazepine Derivatives as anti-Alzheimer Agents. J. Mol. Mod. 10, 328-334

  6. Debnath, B., Gayen, S., Basu, A., Ghosh, B., Srikanth, K., and Jha, T. (2004) Quantitative Structure-Activity Relationship Study Using Refractotopological State Atom Indices on Some Neonicotinoid Insecticides. Bioorg. Med. Chem. 12, 6137-6145

  7. Samanta, S., Debnath, B., Gayen, S., Ghosh, B., Basu, A., Srikanth, K., and Jha, T. (2005) QSAR Modeling of Dopamine D2 receptor binding affinity of 6-methoxy benzamides.  Farmaco., 10, 818-825

  8. Basu, A., Gayen, S., Samanta, S., Panda, P., Srikanth K., and Jha T. (2006) QSAR modeling of neonicotinoid insecticides for their selective affinity towards drosophila nicotinic receptor over mammalian α4β2 receptor. Can. J. Chem. 84, 458-463

  9. Biuković, G., Rössle, M., Gayen, S., Mu, Y., and Grüber, G. (2007) Small-angle X-ray scattering reveals the solution structure of the peripheral stalk subunit H of the A1AO ATP synthase from Methanocaldococcus jannaschii and its binding to the catalytic A subunit. Biochemistry 46, 2070-2078

  10. Gayen, S., Vivekanandan, S., Biuković, G., Grüber, G., and Yoon, H. S. (2007) Backbone 1H, 13C, and 15N resonance assignments of subunit F of the A1AO ATP synthase from Methanosarcina mazei Gö1. Biomol. NMR Assign. 1, 23-25

  11. Gayen, S., Vivekanandan, S., Biuković, G., Grüber, G., and Yoon, H. S. (2007) The NMR solution structure of subunit F of the methanogenic A1AO ATP synthase and its interaction with the nucleotide-binding subunit B. Biochemistry. 46, 11684-11694

  12. Gayen, S., Balakrishna, A. M., Biuković, G., Yulei, W., Hunke, C. and Grüber, G. (2008) Identification of critical residues of subunit H in its interaction with subunit E of the A-ATP synthase from Methanocaldococcus jannaschii. FEBS J. 275, 1803-1812

  13. Rishikesan, S., Thaker, R. Y., Priya, R., Gayen, S., Manimekalai, M. S. S., Hunke, C. and Grüber, G. (2008) Spectroscopical identification of residues of subunit G of the yeast V-ATPase in its connection with subunit E. Mol. Mem. Biol. 25, 400-410

  14. Priya, R., Tadwal, V. S., Rössle, M., Gayen, S., Hunke, C., Peng, W. C., Torres, J. and Grüber, G. (2008) Low resolution structure of subunit b (b22-156) of Escherichia coli F1FO ATP synthase in solution and the b-d assembly. J. Bioenerg. Biomembr. 40, 245-255

  15. Rishikesan, S., Gayen, S., Thaker, R. Y., Vivekanandan, S., Manimekalai, M. S. S., Yau, Y. H., Greifman Shochat, S. and Grüber, G. (2009) Assembly of subunit d (Vma6p) and G (Vma10p) and the NMR solution structure of subunit G (G1-59) of the Saccharomyces cerevisiae V1VO ATPase. Biochim. Biophys. Acta-Bioenergetics 1787, 242-251

  16. Biuković, G.1, Gayen, S.1, Pervushin, K. and Grüber, G. (2009) The domain features of the peripheral stalk subunit H of the methanogenic A1AO ATP synthase and the NMR solution structure of H1-47. Biophys. J. 97, 286-294

  17. Gayen, S., Balakrishna, A. M. and Grüber, G. (2009) NMR solution structure of the N–terminal domain of subunit E (E1-52) of A1AO ATP synthase from Methanocaldococcus jannaschii. J. Bioenerg. Biomembr. 41, 343-348

  18. Priya, R., Biuković, G., Gayen, S., Vivekanandan, S., and Grüber, G. (2009) Solution structure, determined by nuclear magnetic resonance, of the b30-82 domain of subunit b of Escherichia coli F1FO ATP synthase. J. Bacteriology 191, 7538-7544

  19. Gayen, S. and Grüber, G. (2010) Disulfide linkage in the coiled-coil domain of subunit H of A1AO ATP synthase from Methanocaldococcus jannaschii and the NMR structure of the C-terminal segment H85-104. FEBS Lett. 584, 713-718

  20. Raghunathan D., Gayen, S., Grüber, G. and Verma, C. (2010) Crosstalk along the stalk: Dynamics of the interaction of subunits B and F in the ATP synthase of Methanosarcina mazei Gö1. Biochemistry, 49: 4181-90

  21. Manimekalai, M. S. S., Balakrishna, A. M., Hunke, C., Gayen, S., Rössle, M., Jeyakanthan, J. and Grüber, G. (2010) Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A1AO ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering. J. Bioenerg. Biomembr. 42, 311-320

  22. Basak, S., Gayen, S., Thaker, Y. R., Manimekalai, M. S. S., Roessle, M., Hunke, C., and Grüber, G. (2011) Solution structure of subunit F (Vma7p) of the eukaryotic V1VO ATPase from Saccharomyces cerevisiae derived from SAXS and NMR spectroscopy. Biochim. Biophys. Acta-Biomembranes 1808, 360-368

  23. Basak, S., Gayen, S., Ramalingam, J., Grüber, A., Preiser, R. P., Grüber, G. (2011) NMR solution structure of NBD94483-502 of the nucleotide binding domain of the Plasmodium yoelii reticulocyte binding protein Py235. FEMS Microbiol. Letters, 318, 152-158

  24. Raghunathan, D., Gayen, S., Kumar, A., Hunke, C., Grüber, G., and Verma, C. (2012) Subunit F modulates ATP binding and migration in the nucleotide-binding subunit B of the A1AO ATP synthase of Methanosarcina mazei Gö1. J. Bioenerg. Biomembr. 44, 213-224

1 (Authors have equal contribution)


last update 22-May-2018