| Course Title | Pathology (病理学) | ||
| Course Code | BS3104 | ||
| Offered | Study Year 3, Semester 2 | ||
| Course Coordinators | Alvin Lim Soon Tiong (Dr) | stlim@ntu.edu.sg | 6592 1732 |
| Lim Yin Jia (Ms) | limyj@ntu.edu.sg | 6592 1729 | |
| Frederick Koh (Mr) | frederickkoh@ntu.edu.sg | 6592 3505 | |
| Pre-requisites | BS2001 OR BS1016 | ||
| AU | 3 | ||
| Contact hours | Lectures: 39 | ||
| Approved for delivery from | |||
| Last revised | 16 Dec 2022, 13:33 | ||
This course aims to introduce the range and spectrum of disease conditions encountered in each organ system. You will learn why and how diseases come about, what are the possible clinical manifestations and a better approach to managing and treating patients.
Upon successfully completing this course, you should be able to:
General pathology (comparisons of diseased and healthy organs and cells)
Pathological conditions of the endocrine system including pancreas
Haematolymphoid pathology
Cardiovascualr pathology
Genetic basis of diseases
Respiratory diseases
Diseases of the gastrointestinal tract
Liver and pancreas patholgies
Diseases of the kidney and urinary tract
Breast and skin diseases
Gynaecological and reproductive pathologies
Bone, joint and central nervous system
| Component | Course ILOs tested | SBS Graduate Attributes tested | Weighting | Team / Individual | Assessment Rubrics |
|---|---|---|---|---|---|
| Continuous Assessment | |||||
| Mid-semester Quiz | |||||
| Multiple Choice Questions | 1, 2, 3, 4, 5, 6 | 1. a, b, c, d 2. b 3. a, c, e, g | 40 | individual | |
| Examination (2.5 hours) | |||||
| Short Answer Questions | 1, 2, 3, 4, 5, 6 | 1. a, b, c, d 2. b 3. a, c, e, g 5. c 7. a | 60 | individual | See Appendix for rubric |
| Total | 100% | ||||
These are the relevant SBS Graduate Attributes.
1. Recognize the relationship and complexity between structure and function of all forms of life, resulting from an academically rigorous in-depth understanding of biological concepts
a. Possess a conceptual framework that identifies the relationships between the major domains in the field of biology.
b. Explain the relationship between structure and function of all forms of life at the molecular level
c. Explain the relationship between structure and function of all forms of life at the cellular level
d. Explain the relationship between structure and function of all forms of life at the organism level
2. Critically evaluate and analyze biological information by applying the knowledge, scientific methods and technical skills associated with the discipline
b. Create and evaluate hypotheses
3. Develop and communicate biological ideas and concepts relevant in everyday life for the benefit of society
a. Simplify and explain scientific concepts and results of experiments to a non-biologist (avoiding jargon)
c. Demonstrate an understanding of the recursive nature of science, where new results continually modify previous knowledge
e. Discuss current critical questions in the field of biology
g. Demonstrate an understanding of the history of ideas and development of the major fields of biology
5. Develop communication, creative and critical thinking skills for life-long learning
c. Demonstrate critical thinking skills such as analysis, discrimination, logical reasoning, prediction and transforming knowledge
7. Demonstrate information literacy and technological fluency
a. Locate and evaluate information needed to make decisions, solve problems, design experiments, and understand scientific data
- Lecturer will require students to answer questions in class as a form of revision of the previous lesson, prompt feedback will be provided to you.
- Lecturer will set individual and/or group assignments to submit or present during the next lesson, feedback will be provided directly to you.
- After the mid-term quiz, lecturer will discuss the questions and common mistakes with students.
- After the final exam, an examiner's report submitted by the lecturers will be made available to students for evaluation of your performance.These address all 6 of the intended learning outcomes.
| Lectures (39 hours) | The lectures provide necessary background information for the understanding of pathology which involves the investigation of the causes of disease as well as the underlying mechanism that result in the presenting signs and symptoms of the patient. |
Prescribed Texts
Robbins Basic Pathology, 10e (Robbins Pathology) 10th Edition
by Vinay Kumar MBBS MD FRCPath (Author), Abul K. Abbas MBBS (Author), Jon C. Aster MD PhDReference Texts
The Nature of Disease: Pathology for the Health Professions (Second Edition)
Dr. Thomas H McConnellMuir, Robert, Sir, Muir's textbook of pathology, 14th Edition, Hodder Arnold, 2008. (RB111.M953)
Rubin, Raphael, Rubin's pathology: clinicopathologic foundations of medicine, 6th Edition, Wolters Kluwer Health/Lippincott Williams & Wilkins, 2012. (RB25.R896 2012)
Gardner, R. J. M., Chromosome abnormalities and genetic counseling, 4th Edition, Oxford University Press, 2012. (RB155.7.G228 2012)
Hoffbrand, A. V, Essential haematology, 6th Edition, Wiley-Blackwell, 2011. (RC633.H698 2011)
Huang, Yufang, Bing li xue, 2nd Edition, Zhongguo Zhong yi yao chu ban she, 2007.
(Call no: RB111.B613x 2007)
(1) General
You are expected to complete all assigned pre-class readings and activities, attend all classes punctually and take all scheduled assignments and tests by due dates. You are expected to take responsibility to follow up with course notes, assignments and course related announcements for classes you have missed. You are expected to participate in all class discussions and activities. Please inform the instructors/coordinators of your absence for classes/tests/exams, it is compulsory to provide a valid reason for your absence.(2) Classroom conduct
In order to have engaging discussions and facilitate an open learning environment, it is important that all students in the classroom be treated with respect. Please be tolerant and kind in your approach to your classmates and lecturer. Students are required to give their full attention to the lecturer and any classmates that are speaking, and avoid talking while others are talking.Please ensure your mobile phone is turned on in silent mode so as not to disrupt the instructor and other students. If your phone rings and you must answer it, please wait till you are outside of the classroom before answering the call.
The use of laptops is permitted for reading electronic copies of course materials, taking of notes or supplementing your learning during class activities or discussions. The instructor reserves the right to restrict or deny use if this is abused.
Good academic work depends on honesty and ethical behaviour. The quality of your work as a student relies on adhering to the principles of academic integrity and to the NTU Honour Code, a set of values shared by the whole university community. Truth, Trust and Justice are at the core of NTU’s shared values.
As a student, it is important that you recognize your responsibilities in understanding and applying the principles of academic integrity in all the work you do at NTU. Not knowing what is involved in maintaining academic integrity does not excuse academic dishonesty. You need to actively equip yourself with strategies to avoid all forms of academic dishonesty, including plagiarism, academic fraud, collusion and cheating. If you are uncertain of the definitions of any of these terms, you should go to the Academic Integrity website for more information. Consult your instructor(s) if you need any clarification about the requirements of academic integrity in the course.
| Instructor | Office Location | Phone | |
|---|---|---|---|
| Lim Yin Jia (Ms) | SBS-01s-68 | 6592 1729 | limyj@ntu.edu.sg |
| Alvin Lim Soon Tiong (Dr) | SBS-01s-68 | 6592 1732 | stlim@ntu.edu.sg |
| Frederick Koh (Mr) | 6592 3505 | frederickkoh@ntu.edu.sg |
| Week | Topic | Course ILO | Readings/ Activities |
|---|---|---|---|
| 1 | General pathology I (comparisons of diseased and healthy organs and cells) | 1, 2, 3, 4, 5, 6 | |
| 2 | Genetic basis of diseases and genetic diseases | 1, 2, 3, 4, 5, 6 | |
| 3 | General pathology II | 1, 2, 3, 4, 5, 6 | |
| 4 | Respiratory diseases | 1, 2, 3, 4, 5, 6 | |
| 5 | Liver and pancreas | 1, 2, 3, 4, 5, 6 | |
| 6 | Diseases of the kidney and urinary tract | 1, 2, 3, 4, 5, 6 | |
| 7 | Haematolymphoid pathology | 1, 2, 3, 4, 5, 6 | |
| 8 | Diseases of the gastrointestinal tract | 1, 2, 3, 4, 5, 6 | |
| 9 | Bone, joint and soft tissue pathologies | 1, 2, 3, 4, 5, 6 | |
| 10 | Breast and skin diseases | 1, 2, 3, 4, 5, 6 | |
| 11 | Pathological conditions of the endocrine system including pancreas | 1, 2, 3, 4, 5, 6 | |
| 12 | Gynaecological and reproductive pathologies | 1, 2, 3, 4, 5, 6 | |
| 13 | Cardiovascular pathology | 1, 2, 3, 4, 5, 6 |
In this assessment, you will given some case studies with questions to test your ability to analyse the medical cases involving diseases, to diagnose the disease and explain the likely causes, and answer relevant questions pertaining to the case.
| No. of marks | 0-9 | 10-14 | 15-20 |
|---|---|---|---|
| Description | Student show little to no understanding of the topic and is barely able to identify/describe/diagnose the condition in the question. | Student shows moderate to good understanding of the topic and is able to identify / describe / diagnose the condition in the question. Student is able to provide certain understanding of the disease. | Student shows thorough understanding of the topic and is able to identify / describe / diagnose the condition in the question. Student is able to provide in depth understanding of the disease. |
As a result of this course, it is expected you will develop the following "big picture" attributes:
Appreciate the social implications of various diseases in certain cultural and religious contexts
Develop a more holistic approach to disease by combining Western and Eastern approaches to disease diagnosis
Develop confidence in bilingual communication