Dr. Lim Jack Wee, PhD

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PhD Thesis:

Understanding protein structure-function relationship by NMR spectroscopy, NUS/Singapore

Publications:

1. Lim, J., Kong, R., Murugan, E., Ho, C. L., Liang, Z.-X., and Yang, D. (2011) Solution Structures of the Acyl Carrier Protein Domain from the Highly Reducing Type I Iterative Polyketide Synthase CalE8. PLoS ONE 6, e20549
2. Fan, J.-S., Lim, J., Yu, B., and Yang, D. (2011) Measurement of amide hydrogen exchange rates with the use of radiation damping. J. Biomol. NMR 51, 151-62
3. Lim, J., Sun, H., Fan, J.-S., Hameed, I. F., Liang, Z.-X., Lescar, J., Yang, D. (2012) Rigidifying acyl carrier domain does not affect its function in iterative type I polyketide synthase CalE8. Biophys. J. 103, 1037-44
4. Priya, R., Biuković, G., Manimekalai, M. S. S., Lim, J., Rao, S. P. S., and Grüber, G. (2013) Solution structure of subunit γ (γ1-204) of the Mycobacterium tuberculosis F-ATP synthase and the unique loop of γ165-178, representing a novel TB drug target. J. Bioenerg. Biomembr. 45, 121-129
5. Lim, J., Shen, Y., Martin, G., Winkler, C., Yang, D. (2013) Structure-function analysis of full-length midkine reveals novel residues important for heparin-binding and zebrafish embryogenesis. Biochem. J. 451, 407-415
6. Basak, S., Lim, J., Manimekalai, M. S. S., Balakrishna, A. M., and Grüber, G. (2013) Crystal- and NMR structures give insights into the role and dynamics of subunit F of the eukaryotic V-ATPase from Saccharomyces cerevisiae. J. Biol. Chem. 288, 11930-11939

¹ (Authors have equal contribution)