Prof. Dr. Ünal Coskun

Paul Langerhans Institute, Technical University Dresden

Germany

Diploma Thesis:

Structural and Functional Characterization of the A1 ATPases from Methanosarcina mazei Gö1 and Isolation of the F1 ATPase of Acetobacterium woodi. Degree in 2001

PhD Thesis:

Kopplungsmechanismus im A1-Komplex und 2- und 3D-Rekonstruktion der A-ATPase aus methanogenen Bakterien mittels Einzelpartikelanalyse von elektronenmikroskopischen Bildern. Degree in 2005

Publications:

1. Grüber, G., Svergun, D., Coskun, Ü., Lemker, T., Koch, M. H. J., Schägger, H. and Müller V. (2001) Structural Insights into the A1 ATPase from the Archeon, Methanosarcina mazei Gö1. Biochemistry 40, 1890-1896

2. Schäfer, H.-J., Coskun, Ü., Eger, O., Godovac-Zimmermann, J., Wieczorek, H., Kagawa, Y. and Grüber, G. (2001) 8-N3-3'-biotinyl-ATP, a novel monofunctional reagent: Differences of the F1 and V1-ATPases by means of the ATP analogue. Biochem. Biophys. Res. Comm. 286, 1218-1227

3. Coskun, Ü., Grüber, G., Koch, M.H.J., Godovac-Zimmermann, J., Lemker, T. and Müller, V. (2002) Crosstalk in the A1-ATPase from Methanosarcina mazei Gö1 due to nucleotide-binding. J. Biol. Chem. 277, 17327-17333 

4. Grüber, G., Godovac-Zimmermann, J., Link, T.A., Coskun, Ü., Rizzo, V.F., Betz, C. and Bailer, S.M. (2002) Expression, purification and characterization of subunit E, an essential subunit of the vacuolar ATPase. Biochem. Biophys. Res. Comm., 298, 383-391

5. Rizzo, V.F.¹, Coskun, Ü.¹, Radermacher, M., Ruiz, T., Armbrüster, A. and Grüber, G. (2003) Resolution of the V1 ATPase from Manduca sexta into subcomplexes and visualization of an ATPase active A3B3EG-complex by electron microscopy. J. Biol. Chem. 278, 270-275

6. Coskun, Ü.¹, Rizzo, V. F.¹, Koch, M. H. J. and Grüber, G. (2004) Ligand-dependent structural changes in the V1 ATPase from Manduca sexta . J. Bioenerg. Biomembr. 36, 249-256

7. Coskun, Ü., Radermacher, M., Müller, V., Ruiz, T. and Grüber, G. (2004) Three-dimensional organization of the archaeal A1 ATPase from Methanosarcina mazei Gö1. J. Biol. Chem., 279, 22759-22764

8. Armbrüster, A., Svergun, D. I., Coskun, Ü., Juliano, S., Bailer, S. and Grüber, G. (2004) Structural analysis of the stalk subunit Vma5p of the Yeast V-ATPase in solution. FEBS Lett., 570, 119-1255

9. Coskun, Ü., Chaban, Y.L., Lingl, A., Müller, V., Keegstra, W., Boekema, E.J. and Grüber G. (2004) Structure and subunit arrangement of the A-type ATP synthase complex from the archaeon methanococcus jannaschii visualized by electron microscopy. J. Biol.Chem., 279, 38644-38648

10. Chaban, Y.L., Coskun, Ü., Keegstra, W., Oostergetel, G. T., Boekema, E.J. and Grüber G. (2004) Structural characterization of an ATPase active F1-/V1-ATPase (α3/β3 E G)hybrid complex. J. Biol.Chem., 279, 47866-47870

11. Müller, V., Lemker, T., Lingl, A., Weidner, C., Coskun, Ü. and Grüber, G. (2005) Bioenergetics of archaea: ATP synthesis under harsh environmental conditions. J. Mol. Microbiol. Biotechnol. 10, 167-180

¹ (Authors have equal contribution)